Pre-Cath Medications
This infographic provides essential guidance on managing medications before cardiac catheterization, focusing on balancing medication safety and procedure outcomes.
Metformin
- eGFR ≥ 60:
- Continue Metformin.
- Rationale: Lower risk of contrast-associated acute kidney injury (AKI).
- eGFR ≤ 45:
- Avoid Metformin.
- Rationale: Increased risk of lactic acidosis peri-cath, though the evidence remains weak.
Glucose-Lowering Medications (e.g., Insulin, Sulfonylureas)
- No history of hypoglycemia:
- Continue as usual.
- Rationale: NPO status can increase the risk of hypoglycemia, but some glucose-lowering agents can be safely continued.
- History of hypoglycemia:
- Hold or reduce the morning dose of these medications.
- Rationale: Sedation and fasting before the procedure heighten hypoglycemia risk.
RAAS Inhibitors (ACEi/ARB)
- eGFR ≥ 60:
- Continue these medications.
- Rationale: The risk of peri-procedure complications is low.
- eGFR < 60:
- Hold 24 hours pre-cath.
- Rationale: RAAS inhibition may reduce GFR, increasing the risk of contrast-induced AKI.
Oral Anticoagulants (OAC, e.g., Warfarin, DOACs)
- Thrombotic risk (e.g., AF, mechanical valve):
- Continue OAC, especially for radial access.
- Rationale: Good evidence supports continuing OAC unless there is high bleeding risk.
- Bleeding risk (e.g., rotational atherectomy, CTO):
- Hold Warfarin and bridge with LMWH if necessary.
- Rationale: Reducing bleeding risk is critical in high-risk procedures.
Created by: Dr. Hirsh Elhence
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