Cardiac Stress Testing

Stress Testing - CardioNerds

Cardiac Stress Testing

This infographic highlights key aspects of cardiac stress testing, comparing multiple modalities and outlining indications for their use.

Indications

  • Evaluation of stable chest pain in patients with intermediate to high CAD risk
  • Risk stratification for new-onset symptoms in patients with known CAD
  • Assessment of valvular heart disease and HCM
  • Evaluation of microvascular disease and coronary vasculopathy in transplant patients
  • Identification of hibernating myocardium in known CAD cases

Types of Stress Testing

  • Exercise Stress Test (Treadmill):
  • Recommended for patients who can exercise adequately to achieve 5 METS and 85% of maximum predicted HR
  • Report analysis includes:
    • Duration of exercise, METS achieved, % max HR, HR/BP response
  • Pharmacologic Stress Testing:
  • Inotropes (e.g., dobutamine) for patients unable to exercise; avoid in ventricular arrhythmias or severe HTN
  • Vasodilators (e.g., adenosine, regadenoson) suitable for most patients but avoided in COPD/asthma or hypotension
  • Note: Avoid caffeine for at least 12–24 hours before testing

Compare & Contrast Stress Modalities

ModalityWho?ProsConsPositive Test
EKGPatients without baseline EKG abnormalitiesEasy, no radiationCannot localize ischemia1-mm horizontal or downsloping ST depression
EchoAbnormal baseline EKG; HCM, AS evaluationEvaluates wall motion, pulmonary HTNPatient-dependent image qualityNew wall motion abnormalities
SPECTKnown CADFunctional assessment of ischemiaLimited in high BMI, radiation exposurePerfusion defects during stress
PETKnown CAD, microvascular diseaseQuantifies blood flow, assesses viabilityExpensive, limited availabilityAbnormal MBFR
MRIHigh clinical suspicion of CADAllows tissue characterizationPatient limitations (e.g., metallic implants)Late gadolinium enhancement

Key Recommendations

  • Exercise testing is preferred if the patient can reach the required workload.
  • Use pharmacologic testing for those with physical limitations.
  • Review the duration of exercise, METS, and HR/BP response for meaningful insights.

Created by Dr. Gurleen Kaur
Reviewed by Dr. Simrat Kaur, Dr. Amit Goyal, and Dr. Jessie Holtzman


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