Infographics

Defibrillation Thresholds & Desmoplakin Cardiomyopathy

Defibrillation Thresholds & Desmoplakin Cardiomyopathy This infographic explores Defibrillation Thresholds (DFTs) and their importance in device management for cardiomyopathy patients, as well as the role of Desmoplakin (DSP) mutations in hereditary cardiomyopathy, especially ARVC. It covers the indications for DFT testing, causes of high DFTs, genetic implications in unexplained DCM…

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ATTR Amyloid Cardiomyopathy

ATTR Amyloid Cardiomyopathy This infographic covers the key aspects of ATTR Amyloid Cardiomyopathy, emphasizing the importance of suspecting amyloid in heart failure cases with certain clinical signs. It details amyloid etiology, including hereditary and non-hereditary forms, and highlights the necessity of considering AL amyloid in differential diagnoses. Multi-modal diagnostic approaches…

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Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic heart muscle disorder that primarily affects the right ventricle. The 2010 revised task force established diagnostic criteria, using six factors to classify cases as definite, borderline, or probable based on major and minor criteria. Diagnostic…

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Takotsubo Stress Cardiomyopathy

Takotsubo: Understanding Broken Heart Syndrome SummaryTakotsubo cardiomyopathy, or Broken Heart Syndrome, is a unique condition that mimics a heart attack but differs in etiology and treatment. Named after the Japanese octopus trap that resembles the left ventricle's shape in this condition, Takotsubo predominantly affects older women and is often triggered…

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Cardiac Sarcoidosis

Cardiac Sarcoidosis: Clinical Manifestations, Diagnosis, and Treatment This infographic summarizes key aspects of cardiac sarcoidosis, including clinical presentations, diagnostic tools, and treatment approaches. Clinical Manifestations: Cardiac sarcoidosis may present with conduction blocks, ventricular and atrial arrhythmias, non-ischemic cardiomyopathy, sudden cardiac death, and pulmonary hypertension. Diagnosis: Primary diagnostic tools include: CMR…

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Approach to Diuretic Resistance

Approach to Diuretic Resistance This infographic outlines the mechanisms and management strategies for addressing diuretic resistance in patients, including approaches based on pharmacology, extra-renal, and intra-renal factors. Key management recommendations are included for sequential blockade, acetazolamide, high-dose mineralocorticoid receptor antagonists, hypertonic saline, and SGLT-2 inhibitors Produced by: Dr. Gurleen KaurEdited…

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Mavacampten

Mavacamten: Novel Therapeutic Agent for Obstructive Hypertrophic Cardiomyopathy (HCM) Mavacamten is a new allosteric inhibitor of cardiac myosin ATPase, designed to reduce sarcomere hypercontractility, a key mechanism in obstructive hypertrophic cardiomyopathy. By decreasing actin-myosin cross-bridge interactions, Mavacamten helps to attenuate contractility, relieve left ventricular outflow tract (LVOT) obstruction, and improve…

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The METEORIC-HF Study Infographic

The METEORIC-HF Study: The Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure with Reduced Ejection Fraction Summary:The METEORIC-HF study investigated whether Omecamtiv Mecarbil, a selective cardiac myosin activator, could improve exercise capacity in patients with HFrEF. Results showed no significant improvement in exercise capacity metrics, indicating that…

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