Pathophysiology of Constriction: Intrathoracic-Intracardiac Dissociation

This infographic explores the unique hemodynamic changes in constrictive pericarditis, focusing on intrathoracic-intracardiac dissociation. It highlights how, under normal conditions, intrathoracic pressure variations during respiration are equally transmitted to both the heart chambers and the pulmonary vasculature. In contrast, constriction limits this transmission to the heart chambers, altering the mitral inflow gradient, particularly during inspiration. This pathophysiological feature is key to understanding the clinical presentation and management of constriction.

Produced by: Dr. Evelyn Song
Graphics by: Dr. Karan Desai

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