Family History of Premature ASCVD: FAQs in CVD Prevention Clinic

A family history of premature ASCVD (atherosclerotic cardiovascular disease) includes events such as heart attack, stroke, or other cardiovascular incidents in first-degree relatives under age 55 for men or under 65 for women. This history is a risk-enhancing factor, especially for patients with borderline to intermediate ASCVD risk scores.

Despite genetic predispositions, lifestyle changes like healthy eating, regular exercise, quitting smoking, and controlling blood pressure and cholesterol (AHA’s “Life’s Simple 7”) can significantly reduce CAD risk. Additional tools, such as the coronary artery calcium (CAC) score and lipoprotein (a) levels, assist in risk assessment and guide shared decision-making around statin therapy for patients with a family history of premature ASCVD.

Produced by: Dr. Ahmed Ghoneem
Edited by: Dr. Colin Blumenthal and Dr. Ann Marie Navar

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